Which of the following is true regarding tissue specimens?

The statement about tissues for genetic analysis not being placed in formalin is accurate because formalin, which is a common fixative used to preserve tissue specimens, can cross-link proteins and nucleic acids. This fixation process can interfere with the quality and integrity of the DNA and RNA, making it unsuitable for genetic studies that require intact and unmodified genetic material. For genetic analysis, fresh or snap-frozen tissues are often preferable, as they help preserve the molecular integrity necessary for accurate testing.

Other options touch on different aspects of tissue handling and procedures. For example, re-collecting tissue specimens can be challenging, especially if the material is critical or the procedure is invasive. Biopsy procedures, while informative, can sometimes carry significant costs depending on the setting and methods used. Minimal disturbance is generally a best practice in handling specimens, but it does not specifically address the unique requirements for genetic analysis. Thus, the most accurate statement in relation to the integrity required for tissue samples in genetic studies is that tissues for genetic analysis should not be placed in formalin.